Combination Prevention of HIV: A Technical Guide to Working with Key Affected Populations

This practical guide presents evidence and example activities that serve as a resource for program implementers and planners working to prevent HIV among female sex workers, men who have sex with men, and people who inject drugs. Designing integrated structural, biomedical, and behavioral approaches that are tailored to address the specific drivers of these key affected populations’ risk is critical, particularly given the powerful role that vulnerabilities at the societal, programmatic, and individual levels play in defining individual and community risk of infection. When applied with the necessary balance, intensity, quality, and coverage, these integrated approaches have the best chance for a sustainable impact. This resource offers guidance on a range of structural, biomedical, and behavioral interventions, including those that address: advocacy, stigma and discrimination, HIV care and treatment, PEP, STI management and diagnosis, PMTCT, peer education, harm reduction, and many more.

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