Skip to content

Story and Perspective

Empowering Girls and Young Women: The Key to Achieving an AIDS-free Generation

By: Joram Luke, Senior Technical Advisor, HIV/AIDS & SRHR

Photo: Ricardo Franco

This article first appeared in the MediaplanetUSA Living With HIV and AIDS campaign, which was published in USA Today and online on Future of Personal Health.


As we strive for a world free from HIV and AIDS, we must confront a sobering reality: The burden of this disease weighs heavily upon girls and young women, particularly in sub-Saharan Africa. We must expedite interventions to reduce new HIV cases among girls and young women to achieve an AIDS-free generation.

Despite significant progress in combating HIV and AIDS globally, girls and young women in sub-Saharan Africa continue to face challenges in accessing prevention, care, treatment, and support. They continue to suffer from and die from the disease at an alarming rate, although antiretroviral treatment (ART) is widely available in many parts of the world.

In 2022, according to UNAIDS, an estimated 1.9 million adolescent girls and young women aged 15-24 years were living with HIV worldwide, with 82% of those cases in sub-Saharan Africa. This compares to 1.2 million adolescent boys and young men living with HIV in the same age bracket. In sub-Saharan Africa, approximately 6 out of 7 new infections occur among adolescents aged 15-19 years, and young women ages 15-24 are twice likely to be living with HIV compared to their male counterparts.

Client holds HIV/AIDS treatment drugs.
Client holds HIV treatment drugs. Photo: Ricardo Franco

Contributing factors

The vulnerability of girls and young women to HIV is influenced by a mix of social, economic, and cultural factors. Gender inequality directly correlates with the vulnerability of girls and young women to HIV. Girls and young women often lack the autonomy to negotiate safe sexual practices, and with diminished access to comprehensive sex education, lack the knowledge to make informed decisions about their sexual health.

Girls and young women without money sometimes engage in transactional sex or become dependent upon their partners, exacerbating their vulnerability to HIV. Early marriage and early sexual debut expose girls to sexual relationships at a young age, often with older partners who may carry a higher HIV risk. Gender-based violence also heightens HIV risk.

Limited access to healthcare, including lack of transportation, financial constraints, provider bias, and stigma hinder girls and young women from accessing prevention, care, and treatment.

Addressing inequality, increasing access

To achieve the UNAIDS 95-95-95 targets, we must address the unique needs and circumstances of girls and young women. We can do this by borrowing from the success of the DREAMS initiative. The DREAMS interventions include access to: HIV testing, treatment, and prevention tools, such as pre-exposure prophylaxis and ART to reduce transmission; comprehensive sex education, including skills for negotiating safer sex practices, condom use, and partner communication; and economic empowerment programs and educational initiatives.

At the same time, DREAMS strengthens the delivery of healthcare services and mobilizes communities to address gender-based violence and harmful gender norms.

Addressing the HIV burden among girls and young women requires more than just resources; it requires political will and commitment. Governments, international organizations, and civil society organizations must prioritize the needs of girls and young women in HIV programs and policymaking. Only through collective action and solidarity can we create an environment conducive to ending the HIV epidemic.

The time to act is now. We cannot afford to ignore the high HIV burden among girls and young women any longer. By prioritizing their needs and rights in our HIV response, we can chart the path toward an AIDS-free generation.

Featured Stories & Perspectives

Seema Kumari, a Yuvakaar in Bihar state

Yuvakaars: Pathfinder India’s Scalable Social Entrepreneurship Model for Rural Health Care 

Through Pathfinder India’s innovative social entrepreneurship model in rural India, young couples delivered quality health products and services to underserved and…

Read More

International Youth Day 2026: Different Contexts, Common Aspirations

Celebrating International Youth Day 2026  Ask a group of adolescents what they hope for their future, and their answers are often remarkably…

Read More

Then Vs Now: Women’s Leadership and Redefining Success

In the quest for gender equality and establishing women’s leadership roles, understanding the unique challenges women face is pivotal. In…

Read More
Mozambique - Youth reached through Mais Escolhas, January 2026.

Mozambique: Community-led Action against a Rising Tide

Mozambique’s famous coastline, one of the longest in Africa, stretches more than 2,300 kilometers (1,430 miles) along the Indian Ocean.…

Read More

Delivering Context-Specific Maternal Health Solutions in Fragile and Insecure Settings

When a woman dies from preventable complications during childbirth, it signals a systemic failure. In fragile and conflict-affected settings, these vulnerabilities…

Read More

How Women are Harnessing Jordan’s Green Economy

Jordan’s growing green economy is creating new conversations around sustainability, innovation, and climate resilience—at the same time, it is also…

Read More
An Innovative Mobile Strategy for Changing Perceptions of Family Planning in Kwilu Province, DRC

An Innovative Mobile Strategy for Changing Perceptions of Family Planning in Kwilu Province, DRC  

Aller à la traduction en français >> A Golden Opportunity Vincent Aseme Talasi, 42, is a father to six children.…

Read More

Dissolving Mistrust through Dialogue: How the RMA Model Transformed the Life of a Couple in Niger

Jump to English translation. Dissiper la méfiance par le dialogue Comment le modèle RMA a transformé la vie d’un couple…

Read More

New Podcast: The Springboard!

Women Building What the World Was Missing In our inaugural episode of the Springboard podcast, we gathered visionary leaders who…

Read More

Investing in Women | Pathfinder Annual Report 2025

For this Country-Led in Action newsletter edition, we are sharing our 2025 annual report! The progress, programs, and innovations showcased…

Read More

Beyond Participation: Ensuring Women & Communities Lead Climate Resilience

To truly build resilience in the face of the climate crisis, we must shift the power dynamics: from top-down interventions to community-led transformation—with…

Read More
Clinical Mentorship for Better Family Planning Care

From Fear to Mastery: Clinical Mentorship for Better Family Planning Care

I Used to Fear it. Now I Master it. KIKWIT, Democratic Republic of the Congo — For years, women in Kwilu Province…

Read More